blood plasma slideshare

Human Anatomy & Physiology: Blood & Hematology; Ziser Lecture Notes, 2014.4 2 Composition: plasma 55% of volume formed elements 45% Plasma the liquid portion of blood clear straw colored fluid plasma consists of: liquid solvent (water) 93% solutes (7%) 1000’s of different solutes most solutes are proteins (=plasma proteins) The plasma is … Overview of Blood A few thoughts on work life-balance 1y ago, 1,670,300 views 1y ago, 1,670,300 views Like A few thoughts on work life-balance SlideShare. Canadian Blood Services is working towards a more integrated relationship with hospital customers to provide reliable, accessible and sustainable products and services for patients. The upper liquid layer, called plasma, represents about 55% of the volume of whole blood. BLOOD PRODUCTS & PLASMA SUBSTITUTES - SlideShare Plasma also plays a role in transporting red blood cells and other components throughout the body as it also helps in eliminating waste products from the circulation. Whole blood, plasma, and serum are the major blood matrices with a high abundance of proteins. The ABO and Rh blood systems are discussed in detail below. Single Blood Bag 1050*0.55 = 578 mL plasma/min: Glomerular filtration rate: 110: The GFR is the amount of plasma entering Bowman’s capsule per minute. Plasma amino acids is a screening test done on infants that looks at the amounts of amino acids in the blood. FUNCTION OF HAEMOGLOBIN When there is a high concentration of oxygen e.g in the alveoli haemoglobin combines with oxygen to form oxyhaemoglobin. section 2, chapter 14: blood plasma - SlideShare Indications for blood and blood product transfusion Whole blood, plasma, and serum are the major blood matrices with a high abundance of proteins. Drug Distribution to Tissues. Plasma makes up 55% of the blood. Alternative Names. Peripheral blood from 22 healthy male and female volunteer donors (20-54 years old) was collected using 4.5 mL blood collection tubes containing 0.5 mL citrate solution (VacutainerW, Ref: 369714; BD Biosciences). By volume, the RBCs constitute about 45% of whole blood, the plasma about 54.3%, and white blood cells about 0.7%. Amino acids blood test. For orally administered drugs, remember that the blood supply draining the gut passes through the liver before reaching the systemic circulation. Local blood flow is a strong determinant of the rate of absorption because it continuously maintains the concentration gradient necessary for passive diffusion to occur. Plasma is conventionally prescribed to replace coagulation factors in patients receiving massive transfusion (>one blood volume or 70 ml/kg in 24 h or >50% of blood volume in 3 h), for urgent reversal of the effect of warfarin, in known coagulation factor deficiency, and in cases of thrombotic thrombocytopaenic purpura. 24. Blood is collected from study participants for a variety of purposes, including as a source of DNA, and for a variety of laboratory analyses that may be done on whole blood or blood fractions, including serum, plasma, and lymphocytes. This increased osmotic pressure of plasma and reduced blood pressure will increase the rate of absorption from the tissue fluid, and thus blood volume will be kept constant. Plasma and interstitial fluid are the major components of ECF. 2 Most of this 50% increase occurs by 34 weeks’ gestation and is proportional to the birthweight of the baby. Higher plasma yield for increases in line sensitivity. plasma: The straw-colored or pale yellow liquid component of blood in which blood cells are suspended. hemoglobin: The iron-containing substance in red blood cells that binds to and transports oxygen from the alveoli of the lungs to the tissues of the body. The pH (or the amount of hydrogen ions (H+) in a solution) level of the blood is important in ensuring the proper functionality of biological systems 2. According to the ABO blood group system, there are four blood groups, namely A, B, AB and O.. A–blood group: It possesses A-surface antigens are present on the RBC membrane, and the antibodies in the blood plasma are anti-B type. White blood cells (leukocytes) - help fight infections and aid in the immune process. It is the major component of β Globulins. 8:8-12.3(c). Plateletpheresis - The removal of platelets from a donor, followed by the return of the red blood cells and sometimes the plasma to the donor. Blood samples were run by choosing RCF from 240 to 400×g, time from 8 to 19 min and temperature from 8° to 16°C. The blood is further separated into the various components, such as red cells, plasma, platelets and/or Cryoprecipitated Antihaemophilic Factors (frozen blood). ; B–blood group: It possesses B-surface antigens are present on the RBC membrane, and the antibodies in the blood plasma are anti-A type. … Like all connective tissues, it is made up of cellular elements and an extracellular matrix. The main function of blood is to deliver oxygen and nutrients to various cells and tissues of the body. Blood plasma is composed primarily of 91% water and 7% protein (Albumin-60% of the plasma proteins; 36% immunoglobulin and 4% of fibrinogen). Blood is a liquid tissue. Main Difference – Plasma vs Interstitial Fluid. Plasma was obtained by centrifuging the blood at 2000 rpm for 10 min. Therapeutic drug monitoring (TDM) is generally defined as the clinical laboratory measurement of a chemical parameter that, with appropriate medical interpretation, will directly influence drug prescribing procedures [].Otherwise, TDM refers to the individualization of drug dosage by maintaining plasma or blood drug concentrations within a … Plasma was obtained by centrifuging the blood at 2000 rpm for 10 min. The blood is centrifuged at 3000revs/min and the supernatant plasma removed. 23. The level of glucose circulating in blood at a given time is called as blood glucose level. Fibrin monomers come from an inactive precursor called fibrinogen. blood synonyms, blood pronunciation, blood translation, English dictionary definition of blood. Plasma is the blood fluid that contains blood clotting agents. All other reagents were of analytical grade. Single Blood Bag . The main function to transport Fe ion to tissue where it is required +2 like bone marrow 4. Volume of serum is less in comparison to plasma. Blood sampling techniques (concerning tissues to sample, sample times, or analytical methods) may affect measurement of plasma concentrations. … PLASMA COMPONENTS • Plasma is the aqueous part of blood and can be derived from the separation of a whole blood collection or by apheresis collection. 1unit of packed cell increases the level of hemoglobin by 1g/dl and hematocrit by 3%. Globulins can further be divided into α1, α2, β1, β2, and γ-globulins. By volume, the RBCs constitute about 45% of whole blood, the plasma about 54.3%, and white blood cells about 0.7%. It performs various functions in the body. neutrophils. Ability to separate larger volume blood samples so that less material can be used in new designs. In addition to the A and B antigens, there is a protein called the Rh factor, which can be either present (+) or absent (–), creating the 8 most common blood types ( A+, A- , B+, B- , O+, O- , AB+, AB- ). The blood glucose level varies at different time on various part of the day. Absorption. Blood is a red colour pigment that circulates in the body. Fresh frozen plasma (FFP) FFP is usually transfused to restore or to maintain the clotting mechanism or as a volume replacement when crystalloids and colloids are not used. Packed red cells re used when whole blood may overload the circulation e.g. B. It contains plasma, red blood cells, white blood cells, and platelets. B. Also, regulates the concentration of free iron in plasma 6. Thompson MA, et al. Renal plasma flow equals the blood flow per minute times the hematocrit. Plasma protein binding; many drugs reversibly bind to albumin, α1-acid Designed with hemolysis prevention in mind. The upper liquid layer, called plasma, represents about 55% of the volume of whole blood. The lower layer consists of red blood cells (erythrocytes), white blood cells (leukocytes), and blood platelets (thrombocytes). Collectively, these are called the formed (cellular) elements and represent about 45% of the volume of whole blood. Clots are made from fibers (polymers) of a protein called fibrin. releasing only those blood products and blood which fulfil the desired standards in terms of safety and efficacy. Most oxygen—98.5 percent—is bound to a protein called hemoglobin and carried to the tissues. A blood is decided based on the presence of antigens on the surface of red blood cells. Plasma is made of 90% water and 10% proteins, lipids, carbohydrates, amino acids, antibodies, hormones, electrolytes, waste, salts, and ions Blood cells make up the remaining 45% of the blood. releasing only those blood products and blood which fulfil the desired standards in terms of safety and efficacy. If a person has a hematocrit of 45, then the renal plasma flow is 55 percent. Introduction: The plasma protein binding of drugs and metabolites is known to influence their pharmacokinetics and, therefore, their effects. ("blood-brain barrier"); capillaries of liver and kidney more porous. Although oxygen dissolves in blood, only a small amount of oxygen is transported this way. Components include Plasma proteins, Dissolved gass… A person has 5 - 6 liters of blood in their body. Blood sampling techniques (concerning tissues to sample, sample times, or analytical methods) may affect measurement of plasma concentrations. Hospital Customer Service. Inclusion of additive solution helps extend the shelf life of red cells to 42 days. If a person has a hematocrit of 45, then the renal plasma flow is 55 percent. 2. ... Ionized drugs in general will remain in the plasma and interstitial compartments . Collectively, these are called the formed (cellular) elements and represent about 45% of the volume of whole blood. Amino acids are the building blocks for proteins in the body. Inclusion of additive solution helps extend the shelf life of red cells to 42 days. ABO blood Group system. For instance, a cluster of proteins collectively referred to as the protein C system inactivates clotting factors involved in the intrinsic pathway. biologic products, and their metabolites) and biomarkers in a given biological matrix (e.g. Blood is a circulating tissue composed of fluid, plasma, and cells. 3. Blood samples were run by choosing RCF from 240 to 400×g, time from 8 to 19 min and temperature from 8° to 16°C. blood, plasma, serum, or urine) are critical for the successful conduct of nonclinical, biopharmaceutics, How the Test is Performed. equipment coming in contact with the blood or plasma must have been sterilized in the autoclave at 121.5° C. (15 pounds pressure for at least 20 minutes) i.e., each part of the material to be sterilized must attain this temperature for at least the full 20 minutes. Early high titer plasma therapy to prevent severe COVID-19 in older adults. There are four major blood groups determined by the presence or absence of two antigens, A and B, on the surface of red blood cells. Most of the time, blood is drawn from a vein located on the inside of the elbow or the back of the hand. Blood plasma is actually the dominant component of blood and contains the water, proteins, electrolytes, lipids, and glucose. More blood – more plasma – more analytes – higher sensitivity. Plasma Plasma is a pale yellow coloured liquid component of a blood that holds the cellular elements of blood in suspension. Cutoff values for sample assessment were defined (plasma, ≤0.085 μg/mL; serum, ≤0.154 μg/mL). Makes up 55% of blood volume 3. • Serum is the top clear liquid portion The basis of ABO grouping is of two antigens- Antigen A and Antigen B. Elimination. You may be most familiar with the typical whole blood donation drive seen at workplaces, schools and community events, but there are a few other ways to help give more life through the Red Cross. Blood consists of two main parts – a fluid portion (called plasma, which contains the dissolved ions and molecules) and a cellular portion (the red blood cells, white blood cells and platelets). Plateletpheresis - The removal of platelets from a donor, followed by the return of the red blood cells and sometimes the plasma to the donor. Plasma is also responsible for maintaining adequate fluid balance. 1. Overview. Biotechnology of Blood presents research on applications of biotechnology to blood and its components. Blood cell partitioning has a similar relevance. The plasma from whole blood is typically diluted with 1 part CPD anticoagulant to 4 parts plasma and ends up as units of 250 to 300 mL of 80% plasma. The optimal pH level of the blood is 7.4, which is maintained by three different types of buffer systems working in the body 2.The addition of an acid or a base to a substance changes its pH level. Several circulating plasma anticoagulants play a role in limiting the coagulation process to the region of injury and restoring a normal, clot-free condition of blood. Describe how oxygen is bound to hemoglobin and transported to body tissues. Plasma volume increases progressively throughout normal pregnancy. Blood cells are classified into the following types: Fresh frozen plasma is prepared by removing plasma from a unit of blood within 6 hours of collection and snap freezing at -70oC and storing at - 30C. 2. 2. For ABO subgroups: use specific antisera (e.g. COMPOSITION OF BLOOD Plasma Red blood cells White blood cells Platelets Centrifuged blood. Renal plasma flow equals the blood flow per minute times the hematocrit. fluids. Blood collected in an anticoagulant can be stored and transfused to a patient in an unmodified state. It makes up about 55% of total blo… SlideShare uses cookies to improve functionality and performance, and to provide you with relevant advertising. So blood sugar levels are an important parameter for the study of diabetes. Blood or Bloods A member of a tribe of the Blackfoot confederacy inhabiting southern Alberta. Apheresis is used to extract one cellular component, returning the rest of the blood to the donor. platelets or thrombocytes. A person can donate blood every 90 days (3 months). The cellular elements—referred to as the formed elements—include red blood cells (RBCs), white blood cells (WBCs), and cell fragments called platelets.The extracellular matrix, called plasma, makes blood unique among connective tissues … Plasma is the liquid portion of blood 2. If such units are frozen within 8 hours of collection, they can be called fresh-frozen plasma (FFP) and if longer than 8 hours but less than 24 hours, they are called frozen plasma (FP). JAMA Oncology, 2021. Hexokinase kit was obtained from Sigma Chemical Company USA and GOD-POD from Accurex, India. The components of human blood are: Plasma, in which the blood cells are suspended, including: Red blood cells (erythrocytes) - carry oxygen from the lungs to the rest of the body. However, blood can be used more effectively if it is processed into components, such as red cell concentrates, platelet concentrates, plasma and cryoprecipitate. Distribution. Plasma: A clear, straw coloured, watery fluid in which several different types of blood cells are suspended. Composition of Blood The blood is made up of cells that are suspended in liquid called plasma. Thus, it is critical to remove these proteins efficiently before LC/MS/MS analysis. INTRODUCTION. • Important elements in plasma include albumin, coagulation factors, fibrinolytic proteins, immunoglobulin, and other proteins. Plasmapheresis - A process in which red blood cells are separated from the plasma of a blood donor and returned to the donor's circulatory system. Save A few thoughts on work life-balance SlideShare. The human blood consists of the components, Red blood cells, White blood cells, Plasma and Platelets. • Whole blood is blood that contains an anticoagulant, and is not separated into the liquid portion and blood cells. State the types of blood cells found in human blood. Blood banks often participate in the process of collecting blood and other procedures such as managing stocks, approving blood requests and updating donation information. The pH (or the amount of hydrogen ions (H+) in a solution) level of the blood is important in ensuring the proper functionality of biological systems 2. Sometimes, the term peak plasma level or maximum plasma concentration (C p max), time for peak plasma level (t Cp, max) and area under plasma drug concentration (AUC) also come into pharmacokinetic consideration (Fig. Dissolution of lipid-soluble drugs in adipose tissue 2. 1050*0.55 = 578 mL plasma/min: Glomerular filtration rate: 110: The GFR is the amount of plasma entering Bowman’s capsule per minute. The optimal pH level of the blood is 7.4, which is maintained by three different types of buffer systems working in the body 2.The addition of an acid or a base to a substance changes its pH level. Conclusions: Unbiased valid monitoring to check for adherence to SOP-dictated time for processing to plasma or serum and/or time to storage of whole blood at 4 °C is now feasible. Joyner MJ, et al. Of all routine blood tests plasma/serum potassium measurement is one of the most sensitive to the effect of hemolysis because red-cell potassium concentration is so much higher than that of plasma (approximately 20 times higher); hemolysis causes a spuriously high plasma potassium concentration. Hexokinase kit was obtained from Sigma Chemical Company USA and GOD-POD from Accurex, India. The platelets are responsible for blood clotting. Libster R, et al. Red blood cells constitute 45 % of blood; plasma is about 54.3% and leukocytes of 0.7%. New Eng J Med, 2021. • Fresh frozen plasma (FFP). Lymph, transcellular fluid, cerebrospinal fluid, intraocular fluid, synovial fluid, pericardial, intrapleural, and peritoneal fluids, and digestive juices are minor components of the ECF. 4. Define blood. Extracellular fluid (ECF) is a body fluid found outside of the cell. These are not ABO discrepancies, but refer to a specific reaction grade with two distinct sets of reactions in, 1. The book is organized into four parts. Blood donations can yield a variety of blood products, including red cells, platelets and plasma. Evaluating the extent and the linearity of protein binding is an essential piece of information that has to be generated during drug development. Blood: Its Composition and Function The blood in our circulatory system is a watery based fluid and consists of two basic components: 1) Plasma (55%) and, 2) Formed elements (45%) Part A: Plasma The Plasma is the light yellow liquid portion of the blood … 2 Most of this 50% increase occurs by 34 weeks’ gestation and is proportional to the birthweight of the baby. The lower layer consists of red blood cells (erythrocytes), white blood cells (leukocytes), and blood platelets (thrombocytes). Differences in tissue/blood ratios at equilibrium 1. Three kinds of granulocytes. Blood: Blood is a fluid connective tissue that circulate continuously around the body, allowing constant communication between tissues distant from each other. A plasma derivative is made from human plasma proteins prepared under pharmaceutical manufacturing conditions, such as: Albumin Coagulation factor concentrates Immunoglobulin In Bangladesh, blood is generally collected in CPDA/CPDA1 blood bags that contain 63 mL Carbon dioxide, Section II. Serum is the water fluid from blood without the clotting factors. Consistency is the hallmark of quality and can be achieved only through the use of Standard Operating Procedures (SOPs) by all staff engaged in blood centres at all times. Plasma is a clear yellow liquid which is 55% of total volume of blood. Plasma- This is the liquid portion of the blood and is comprised of protein molecules, fat, sugar, and water. Part I begins with an overview of the blood business in order to provide background of the industry, to identify problems, and perhaps some solutions that rely on the scientific advances made possible by biotechnology. components (red blood cells, and plasma). Oxygen enters blood in the lungs and is transported to cells. We used Systronics and Hans 202 filter colorimeters; and Beckman double beam Model-25 and Shimadzu micro-flow CL-750 spectrophotometers. 3. Fibrinogen is the plasma protein coagulation factor. We used Systronics and Hans 202 filter colorimeters; and Beckman double beam Model-25 and Shimadzu micro-flow CL-750 spectrophotometers. BIOPHYSICAL CHARACTERISTICS OF THE BLOOD 1) Specific gravity Blood - 1056 (152-1063) kg/m 3 - plasma 1027 - red blood cells 1090 2) Viscosity - water = 1; blood 4-5.4x more Syndrome of hyperviscosity – impairment of microcirculation, hypoxia,... 3) Hematocrit - the percentage of red blood cells in the whole blood Males: 0.44 ±0.05 (44 ±5 %) 1. www.wiki.org/wiki/Plasma Blood plasma Blood plasma is the liquid component of blood, in which the blood cells are suspended. It makes up about 55% of total blood volume. It makes up 3% of +total3 plasma proteins 3. The reversible transfer of a drug between the systemic circulation (blood) and extra-vascular (interstitial) fluids and tissues. Food & Drug Administration (FDA) begins to regulate all 7,000 U.S. blood and plasma centers. When the blood reaches the tissue which have a low concentration of oxygen the haemoglobin dissociates with the oxygen and the oxygen is released into body tissues. Because the expansion in plasma volume is greater than the increase in red blood cell mass, there is a fall in haemoglobin concentration, haematocrit and red blood cell count. Association of convalescent plasma therapy with survival in patients with hematological cancers and COVID-19. Diabetes is a disease related by the abnormal metabolism of blood sugar and defective insulin production. The cellular components of blood are erythrocytes (red blood cells, or RBCs), leukocytes (white blood cells, or WBCs), and thrombocytes (platelets). This is known as ‘whole blood’ transfusion. The ABO system is the principal blood grouping system used for humans which categorises people into one of the following four groups – A, B, AB, or O. Red Blood Cells – in about 3 weeks. • Whole blood is blood that contains an anticoagulant, and is not separated into the liquid portion and blood cells. Plasma is made of 90% water and 10% proteins, lipids, carbohydrates, amino acids, antibodies, hormones, electrolytes, waste, salts, and ions Blood cells make up the remaining 45% of the blood. Red blood cells make up 99% of the blood cells. Key Features: Faster blood absorption and plasma separation. cells, plasma, and platelets. Double Blood Bag CPDA For whole blood collection and separation of 2 different blood components (red blood cells, and plasma) obtained through the process of centrifugation and extraction. 10.1056/NEJMoa2033700. five kinds of white blood cells ( WBC s) or leukocytes. The Red Cross calls for national blood policy, which the federal government sets up in 1974, supporting standardized practices and an end to paid donations. Consistency is the hallmark of quality and can be achieved only through the use of Standard Operating Procedures (SOPs) by all staff engaged in blood centres at all times. Binding of drugs to intracellular sites 3. Body recovers the Blood very quickly: Blood plasma volume– within 24 - 48 hours. Transferrin may also transport+2 Cu & Zn 5. Memorandum to blood establishments: "Exemptions to Permit Persons with a History of Viral Hepatitis Before the Age of Eleven Years to Serve as Donors of … Albumins are the most abundant protein group present in blood plasma. Fact sheets -2. . • Serum is the top clear liquid portion red blood cells ( RBC s) or erythrocytes. Dr Gihan AlHusseini Gawish f 2- Transferrin 1. 5. Because the expansion in plasma volume is greater than the increase in red blood cell mass, there is a fall in haemoglobin concentration, haematocrit and red blood cell count. 106 Plasma concentrations measured from central venous catheters (CVCs) and peripheral veins may be different for some drugs. Most clinical chemistry analytes are found in the plasma. Wim Vanderbauwhede. Colour of blood is red, it is obtained by a substance which is present in it is called hemoglobin. The cells are responsible for carrying the gases (red cells) and immune the response (white). The body of the fibrinogen molecule has caps on … Abstract. Plasma is a clear and yellowish fluid part of the blood. Storage, Typing, And Administration of Whole Blood Plasma volume increases progressively throughout normal pregnancy. Suspended in the watery plasma are seven types of cells and cell fragments. n. pl. Blood is a fluid connective tissue which comprises plasma, various types of blood cells and platelets. 2. Plasmapheresis - A process in which red blood cells are separated from the plasma of a blood donor and returned to the donor's circulatory system. 1. 10.1001/jamaoncol.2021.1799. anti-A2) For weak antigen expression: Incubate at room temperature for 15-30 minutes Share Every company is now a tech company; API's can help stay competitive SlideShare. All other reagents were of analytical grade. Memorandum to blood establishments: "Exemptions to Permit Persons with a History of Viral Hepatitis Before the Age of Eleven Years to Serve as Donors of … Straw colored 4. Peripheral blood from 22 healthy male and female volunteer donors (20-54 years old) was collected using 4.5 mL blood collection tubes containing 0.5 mL citrate solution (VacutainerW, Ref: 369714; BD Biosciences). 4. A plasma derivative is made from human plasma proteins prepared under pharmaceutical manufacturing conditions, such as: Albumin Coagulation factor concentrates Immunoglobulin In Bangladesh, blood is generally collected in CPDA/CPDA1 blood bags that contain 63 mL Blood clotting is the transformation of liquid blood into a semisolid gel. www.wiki.org/wiki/Plasma Blood plasma Blood plasma is the liquid component of blood, in which the blood cells are suspended. Presence of blood group-specific soluble substance (BGSS) in the plasma (associated with stomach and pancreatic cancer) Antibodies in reagent anti-A or anti-B antisera against low-incidence antigens Resolution. BIOPHYSICAL CHARACTERISTICS OF THE BLOOD 1) Specific gravity Blood - 1056 (152-1063) kg/m 3 - plasma 1027 - red blood cells 1090 2) Viscosity - water = 1; blood 4-5.4x more Syndrome of hyperviscosity – impairment of microcirculation, hypoxia,... 3) Hematocrit - the percentage of red blood cells in the whole blood Males: 0.44 ±0.05 (44 ±5 %) The ABO grouping system is classified into four types based on the presence or absence of antigens on the red blood cells surface and plasma antibodies. Plasma contains three major types of proteins: albumins, globulins, and fibrinogens. The blood donation is the most common type among the various donating procedures, during which around one pint of “whole blood” is given out by a donor. The red blood cells are the ones that give blood its identity or ‘type.’. Only 1.5 percent of oxygen in the blood is dissolved directly into the blood itself. Platelets & White Blood Cells – within minutes. Recall that blood is a connective tissue. Thus, it is critical to remove these proteins efficiently before LC/MS/MS analysis. components (red blood cells, and plasma). BLOOD Blood is the most commonly used specimen for testing in the clinical laboratory. 1.Carrier of gases, nutrients, and waste products. Double Blood Bag CPDA For whole blood collection and separation of 2 different blood components (red blood cells, and plasma) obtained through the process of centrifugation and extraction. (g) Blood and blood components for therapeutic purposes shall only be distributed to a New Jersey licensed blood bank unless a nonsurgical situation exists which could not be anticipated and blood and blood components are necessary on an emergency basis to treat a life-threatening situation as specified in N.J.A.C. Blood is a circulating tissue composed of fluid, plasma, and cells. fluids. Plasma Overview 1. The cellular components of blood are erythrocytes (red blood cells, or RBCs), leukocytes (white blood cells, or WBCs), and thrombocytes (platelets). 106 Plasma concentrations measured from central venous catheters (CVCs) and peripheral veins may be different for some drugs. Blood Plasma (55%) Cellular elements (45%) RBCs (erythrocytes) WBCs (leucocytes) Platelets (thrombocytes) 6. akqxmc, CPRS, LoL, ROJw, ObFM, HXx, tCLdeq, ABVA, KESLhM, PhUx, ACuPjo, DZIj, bIHzM, ) - help fight infections and aid in the plasma and interstitial fluid are the major blood matrices with high! 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